Spravato in Daytona Beach: A New Path for Depression Relief

When depression will not lift, there is hope

If you have tried multiple antidepressants without lasting relief, you are not alone. Many adults live with depression that resists standard medication. Spravato is an FDA-approved nasal spray for adults with treatment-resistant depression. It is also approved to rapidly reduce depressive symptoms in adults with major depressive disorder who have acute suicidal ideation or behavior, given together with an oral antidepressant. These approvals reflect evidence that Spravato can begin relieving symptoms in hours to days in some patients, rather than weeks.

At Helping Hand Inc in Daytona Beach, Florida, our team provides careful screening, monitored treatment, and compassionate follow up for eligible adults across Volusia County, including Port Orange, Ormond Beach, DeLand, and New Smyrna Beach.

What is Spravato and how does it work

Spravato is the brand name for esketamine, a form of ketamine delivered as a nasal spray. It acts on the brain’s glutamate NMDA receptor pathway, which is different from the serotonin and norepinephrine targets of most antidepressants. By engaging a new mechanism, Spravato may help when other medications have not. You self-administer the nasal spray in a certified clinic under clinical supervision, then rest comfortably while your care team monitors you.

Who Spravato is for

Spravato is indicated for:

  • Adults with treatment-resistant depression. As of 2025, the FDA label allows use with or without an oral antidepressant, based on your clinician’s judgment.

  • Adults with major depressive disorder with acute suicidal ideation or behavior, used in conjunction with an oral antidepressant for short-term reduction of depressive symptoms. Spravato does not replace the need for higher levels of care when safety requires it.

Who should not receive Spravato

Spravato is contraindicated for people with:

  • Aneurysmal vascular disease or arteriovenous malformation

  • History of intracerebral hemorrhage

  • Hypersensitivity to esketamine, ketamine, or ingredients in the spray

Your clinician will also review your blood pressure, medical history, and other medicines to make sure Spravato is safe for you.

Safety, monitoring, and important warnings

Because Spravato can cause sedation and dissociation, it must be given in a certified setting with observation. Patients are monitored for at least 2 hours with vital signs and pulse oximetry, and you will need a ride home. Do not drive or operate machinery until the next day after a full night’s sleep.

Spravato carries a boxed warning for sedation, dissociation, abuse and misuse potential, and suicidal thoughts and behaviors. Your team monitors for these effects during and after treatment, and you will have a safety plan and close follow up. Spravato is available only through the Spravato REMS program, which is why treatment happens in clinic.

Spravato can raise blood pressure, usually peaking about 40 minutes after dosing and resolving within several hours. Your blood pressure is checked before and after treatment. If your baseline blood pressure is high, your clinician may delay or adjust therapy.

Common side effects include dissociation, nausea, dizziness, headache, anxiety, feeling drunk, vomiting, fatigue, and increased blood pressure. Your care team will explain what to expect and how we keep you comfortable.

What to expect on treatment day at Helping Hand Inc

  1. Arrival and check-in
    You will complete a brief symptom review and blood pressure check. We confirm you have a safe ride home.

  2. Guided self-administration
    A clinician shows you how to use the nasal spray device and stays with you throughout.

  3. Monitored relaxation period
    You will rest in a quiet room for at least two hours. We monitor vitals and how you feel. Many patients prefer soft music, eye masks, or mindful breathing during this period.

  4. Discharge and same-day instructions
    You cannot drive or make safety-critical decisions for the rest of the day. Plan light activities and supportive care at home.

How Spravato fits within your overall care

Medication is one part of recovery. Most people do best when Spravato is integrated with a comprehensive plan that may include talk therapy, sleep and nutrition support, movement, and connection with supportive people. For those in crisis, higher levels of care or hospitalization may be recommended for safety. Spravato is not a substitute when urgent stabilization is needed.

Frequently asked questions

Is Spravato the same as ketamine infusions
Spravato contains esketamine in a nasal spray that is FDA-approved for specific depression indications and is delivered under a REMS program with defined dosing and monitoring. IV ketamine is an off-label infusion of racemic ketamine. Your clinician can discuss the differences and which option fits your goals.

Can I drive after treatment
No. You will need a ride home and should avoid driving or operating machinery until the next day after a full night of sleep.

What if I have high blood pressure
Your blood pressure is checked before dosing. If it is elevated, the team may delay or adjust treatment. Spravato is not appropriate if an increase in blood pressure or intracranial pressure would pose a serious risk.

What side effects should I expect
The most common are dissociation, nausea, dizziness, headache, anxiety, vomiting, feeling drunk, fatigue, and increased blood pressure. We monitor you closely and support you if symptoms occur.

Is Spravato addictive
Spravato has a controlled-substance designation and a boxed warning about abuse and misuse. This is why it is given only in certified clinics with monitoring and follow up. Our prescribing follows strict safety protocols.

Can I continue therapy and lifestyle changes
Yes. Many patients combine Spravato with psychotherapy and healthy routines to strengthen and sustain progress. Your plan is individualized.

Why choose Helping Hand Inc in Daytona Beach

  • Compassionate, evidence-based care that centers your safety and goals

  • Certified clinical setting with private, calm rooms and continuous monitoring

  • Collaborative care planning that coordinates with your therapist, primary care, or psychiatrist

  • Transparent costs and support. We help you navigate benefits, savings programs, and scheduling so you can focus on healing.

Take the next step

If depression has felt impossible, you do not have to carry it alone. Spravato may offer a new path forward.

Serving Daytona Beach, Ormond Beach, Port Orange, New Smyrna Beach, and all of Volusia County.
📞 Call Helping Hand Inc to schedule a confidential Spravato consultation today. We will listen, answer every question, and design a plan that puts hope within reach.

Important safety note: This article is for education only and is not medical advice. Always speak with your clinician to determine if Spravato is appropriate for you and to understand risks, benefits, and alternatives. For full prescribing information, including boxed warnings, talk with your provider and review the FDA label.